Presidential Healthcare center

We provide the same Preventive Executive Physical Program as received by the President of the United States.


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Exercise During Teen Years Linked to Lowered Risk of Cancer Death Later

teen exercise 2Women who exercised during their teen years were less likely to die from cancer and all other causes during middle-age and later in life, according to a new study by investigators at Vanderbilt University Medical Center and the Shanghai Cancer Institute in China.

The study was published online July 31 in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association of Cancer Research.

Lead author Sarah Nechuta, Ph.D., MPH, assistant professor of Medicine in the Vanderbilt Epidemiology Center, said understanding the long-term impact of modifiable lifestyle factors such as exercise in adolescence can have important public health implications for disease prevention over the course of a woman’s life.

“Our results support the importance of promoting exercise participation in adolescence to reduce mortality in later life and highlight the critical need for the initiation of disease prevention early in life,” said Nechuta.Teen exercise 3

The study was designed to ascertain potential associations between adolescent exercise and cancer, cardiovascular disease or other causes of death among women in middle age and later life. The investigators used data from the Shanghai Women’s Health Study, a large ongoing prospective cohort study of 74,941 Chinese women between the ages of 40 and 70. The women enrolled in the study between 1996 and 2000. Each participant was interviewed at enrollment about exercise during adolescence, including participation in team sports, as well as other adolescent lifestyle factors. They were also asked about exercise during adulthood and other adult lifestyle factors and socioeconomic status, and participants were interviewed again every two to three years.

Regular exercise was defined as occurring at least once a week for at least three continuous months. Women who Teen exercise 1reported regular adolescent exercise were also asked how many hours a week they participated and for how many years they had exercised regularly.

“In women, adolescent exercise participation, regardless of adult exercise, was associated with reduced risk of cancer and all-cause mortality,” explained Nechuta.

Participation in team sports during the teen years was associated with a reduced risk of cancer death later in life.

Source: American Association for the Advancement of Science (AAAS)


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Chemicals Considered Safe Alone May Trigger Cancer in Combination

chemicals 2New research shows that 50 chemicals people are exposed to daily, all of which are considered non-carcinogenic, may cause cancer when combined.

The series of studies which comprise the research, worked on by 174 scientists in 28 countries, considered links between 85 common chemicals thought not to cause cancer. Fifty were found to interact at ordinary environmental exposure levels to support cancer-related mechanisms. 

“This research backs up the idea that chemicals not considered harmful by themselves are combining and accumulating in our bodies to trigger cancer and might lie behind the global cancer epidemic we are witnessing,” said Dr. Hemad Yasaei, a cancer biologist at Brunel University London, in a press release. “We urgently need to focus more chemicals 3resources to research the effect of low dose exposure to mixtures of chemicals in the food we eat, air we breathe and water we drink.”

The Nova Scotia-based Getting To Know Cancer put together the task force of scientists for the first-of-its-kind look at the effects of combinations of common chemicals thought not to cause cancer. The organization gathered scientists two years ago as part of the Halifax Project, which created task forces of scientists researching the complexities of cancer and its causes.

William Goodson III, a senior scientist at the California Pacific Medical Center, said the results of the studies show not only chemicals 1that chemicals safe on their own are combining in the air to form mixtures that can cause cancer, but that the way chemicals are tested for safety needs to be changed.

“The way we’ve been testing chemicals — one at a time — is really quite out of date,” Goodson said. “Every day we are exposed to an environmental ‘chemical soup,’ so we need testing that evaluates the effects of our ongoing exposure to these chemical mixtures.”

Source: UPI


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Statins and Lower Cancer Mortality; Risk Cut by Up to a Half

Statin 3Statin use is associated with a significant reduction in cancer mortality, conclude two separate studies, one in women, and the other in men. Both were presented here at the American Society of Clinical Oncology (ASCO) 2015 Annual Meeting.

Specifically, statin use was associated with a 22% reduction in deaths from various cancer types in women and a 55% reduction in deaths from bone/connective tissue cancers. The study in men looked at statin use together with the antidiabetes medication metformin and found a 40% reduction in prostate cancer mortality, with the effect more pronounced in men with obesity/metabolic syndrome.

As for how such an effect is achieved, the researchers speculate that statins interfere with cell growth and metastasis by blocking cholesterol production, thereby affecting molecular pathways and the inflammatory Statinsresponse.

The results in women were presented by Ange Wang, BSE, from Stanford University School of Medicine, in California.

Dr. Wang and colleagues examined data from the Women’s Health Initiative, a 15-year research program involving postmenopausal women aged 50 to 79 years who were enrolled between 1993 and 1998 at 40 centers in the United States.

They determined the association between patients’ never having used statins, current statin use, and past statin use, as well as the incidence and number of deaths from cancer among 146,326 women. The median follow-up period was 14.6 years.

The researchers took into account a number of potential confounding factors, including age, race/ethnicity, statins 2education, smoking, body mass index, physical activity, family history of cancer, and current healthcare provider.

Among the participants, there were 23,067 cases of incident cancer for which complete follow-up data were available. There were 7,411 all-cause deaths, including 5,837 deaths from cancer, 613 cardiovascular deaths, and 961 deaths from other causes. In all, 3,152 cancer deaths were included in the analysis, of which 708 were among current statin users and 2443 among patients who had never used statins.

Source: Medscape

 


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Myocardial Infarction Survivors Face Higher Cancer Risk

Heart attackThe risk of developing cancer is significantly higher in survivors of an acute MI compared to the general population, according to a large Danish national registry study.

“Greater focus on long-term cancer risk is warranted in MI survivors. This could potentially have implications on future patient care for MI patients, outpatient follow-up strategies, and distribution of health care resources,” Morten Winther Malmborg said at the annual meeting of the American College of Cardiology.heart attack 3

He presented a nationwide cohort study including 3,005,734 Danish adults with no baseline history of MI or cancer who were followed for up to 17 years in the comprehensive Danish National Patient Registry. During the study period, 125,926 of these individuals had a nonfatal MI.

The subsequent incidence of cancer in the MI survivors was 167 cases per 10,000 person-years compared with 95 per 10,000 person-years in the control group, reported Mr. Malmborg, a fourth-year medical student at the University of Copenhagen.

Source: Family Practice News


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Lung Cancer Screening

lung cancer 3Lung cancers is the leading cause of cancer related mortality in the United States, with 159,000 deaths estimated in 2014.  Age older than 55 years and smoking are the strongest risk factors for lung cancer.  Smoking cessation is the main intervention to prevent lung cancer in 20% of Americans who continue to smoke, but only 15% of cessation efforts succeed.  Outcomes in lung cancers depend crucially on the stage of diagnosis, with 5-year survival for non-small cell lung cancer estimates at 71% – 90% for stage IA and 42% – 75% for stage IB cases, compared with less than 10% for those diagnosed with stage IV.  Currently only 15% of lung cancer cases are diagnosed at stage I, and large trials have not supported the value of chest radiography or sputum cytology for screening.  Low-dose computed Lung Cancer 1tomography (CT) has emerged as a potentially useful screening method, with 55% – 85% of detected cancers found to be stage I.  Approximately 9 million Americans would potentially be eligible for this screening guideline, divided roughly equally between current smokers and former smokers who have quit within the past 15 years.

Source: JAMA

The Presidential Healthcare Center’s Executive Physicals include cancer screening and tumor marker tracking.


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Two Out Of 3 People Diagnosed With Cancer Survive 5 Years Or More

Cancer 3The report found that the most common cancer sites continue to be cancers of the prostate (128 cases per 100,000 men), female breast (122 cases per 100,000 women), lung and bronchus (61 cases per 100,000 persons), and colon and rectum (40 cases per 100,000 persons). Among these common cancer sites, 5-year relative survival was 97 percent for prostate cancer, 88 percent for breast cancer, 63 percent for colorectal cancer, and 18 percent for lung cancer.

The cancer survivor estimates are from CDC’s National Program of Cancer Registries. CDC scientists reviewed the most recent data on cases of invasive cancers reported during 2011. With the exception of urinary bladder cancer, invasive cancer is defined as cancer that has spread to surrounding normal tissue from where it began.Cancer 2

The authors noted that disparities in cancer incidence still persist, with greater rates among men than women and the highest rates among blacks. Additionally, 5-year relative survival after any cancer diagnosis was lower for blacks (60 percent) than for whites (65 percent).

Data by state show incidence rates for all cancer sites ranged from 374 cases per 100,000 persons in New Mexico to 509 cases per 100,000 persons in the District of Columbia.

Source: CDC

The Presidential Healthcare Center’s Executive Physicals include cancer screening and tumor marker tracking.


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10 Ways to Help Reduce Your Risk of Colon Cancer

Colon 33March is Colorectal Cancer Awareness Month: a perfect time to direct attention to the tail end of your digestive tract. Contrary to what many believe, the colon isn’t an inert hollow tube that simply serves as a reservoir for waste until you can find a toilet. Rather, it’s a complex organ that performs the essential function of facilitating balance of fluid and electrolytes in the body in addition to its role in storing and eliminating waste. Equally important – if not moreso – the colon hosts a crucial ecosystem of bacteria that plays a vital role in health. Unfortunately, many of us fail to appreciate just how central the colon is to our health and survival until something goes wrong.

Colorectal cancer is the second leading cause of cancer deaths in the U.S., claiming the lives of more than 50,000 Americans annually. The vast majority of cases occur in people over age 50, and African Americans have the highest rates of colon cancer incidence among all racial groups. Colon 11

As scary as these stats may sound, a large percentage of cases are preventable. Here are 10 lifestyle changes that may be of benefit in colorectal cancer risk reduction:

  1. Reduce your alcohol intake. When it comes to cancer prevention, less (alcohol) is more. Alcohol use is a known risk factor for colorectal cancer – among other cancers – with risk increasing as alcohol intake increases. If you choose to drink, try limiting your intake to no more than one drink daily.
  2. Quit smoking. Smoking is not just a risk factor for lung cancer, but for all digestive system cancers, including colorectal, stomach and esophageal. Make the decision to quit this month, once and for all.
  3. Get moving! Sedentary lifestyles are associated with an increased risk of digestive system cancers. Evidence supporting a significant protective effect of physical activity on colorectal cancer risk is particularly strong. The body of available research suggests that the most active adults have a 40 to 50 percent  reduced risk of developing colon cancer, compared to the least active adults. Importantly, the protective effect of exercise appears to be independent of weight status, meaning that regular physical activity appears to reduce risk of colon cancer even in people who are overweight or obese. So if regular exercise hasn’t yielded the weight loss you’ve hoped for, don’t be discouraged: There are substantial health benefits to physical activity that may not show up on the scale. Colon 22
  4. Get serious about weight loss. Obesity is a strong risk factor for colorectal cancer, and researchers estimate that risk increases about 15 percent with each five additional points of body mass index beyond the upper end of normal range. So, for example, weight loss that results in a reduction of BMI from 35 to 30 would be expected to result in about a 15 percent risk reduction.
  5. Eat less red meat. There is strong evidence supporting high intake of red meat as a risk factor for colorectal cancer. One large study that examined the diets of adults aged 50 to 71 showed that people with the highest intakes of red meat – an average of 5 ounces per day – had a 24 percent greater risk of developing colorectal cancer compared to those with the lowest intake – an average of about half an ounce per day. It has been proposed that multiple mechanisms may be at play, including the type of iron found in red meat (heme iron) and increased exposure to carcinogens called HCAs that are produced when red meat in particular is charred or cooked at a high temperature. If you can’t imagine life without red meat, try thinking of red meat as a garnish to veggie-heavy meals such as stir fries or salads, rather than a center-of-the-plate affair. And consider lower-temperature cooking methods such as braising, boiling or even sautéing instead of broiling or grilling.Colon 66
  6. Avoid foods preserved with sodium nitrite. As you go about reducing your meat intake, start with “pink” processed meats like bacon, salami and hot dogs. These foods – as well as other processed lunchmeats – are commonly preserved with sodium nitrite. When sodium nitrite encounters stomach acid during digestion, it may convert to a compound called a nitrosamine, which is a known carcinogen. Indeed, both high intake of nitrites and processed meats have been associated with increased risk of colorectal cancer compared to lower intakes. If you choose to consume processed meats, look for nitrite-free products, such as those marketed by the Applegate Farms brand.

 

Read more here: U.S News & World Report